Proteglycan and Development of the Brain. Functions of Brain Chondroitin Sulfate Proteoglycan.
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چکیده
منابع مشابه
Receptor-mediated adhesive and anti-adhesive functions of chondroitin sulfate proteoglycan preparations from embryonic chicken brain.
Chondroitin sulfate proteoglycans inhibit the adhesion of cells to extracellular matrix proteins that otherwise permit adhesion. Although proteoglycans are widely assumed to act by masking the other protein in a mixed substrate, recent studies suggest that proteoglycans inhibit adhesion through mechanisms initiated by their binding to specific cell surface receptors. To explore this issue, we d...
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s, 13th FEBS Meeting, p. 180, Jerusalem, Israel
متن کاملOccurrence of three distinct molecular species of chondroitin sulfate proteoglycan in the developing rat brain.
More than 60% of brain chondroitin sulfate proteoglycans were extracted from 10-day-old rat brains by homogenization in ice-cold phosphate-buffered saline containing protease inhibitors. Although the soluble proteoglycan preparation was a mixture of chondroitin sulfate proteoglycans with a different hydrodynamic size as well as a different molecular density, each subfraction of the proteoglycan...
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Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury.
Injury to the adult mammalian CNS results in reactive changes among the glial cells surrounding the site of damage. Recently, an unusual class of glial cells has been identified within the intact adult rat cerebellum on the basis of the expression of the NG2 chondroitin-sulfate proteoglycan (Levine and Card, 1987). To determine whether the cells that express the NG2 proteoglycan show reactive c...
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ژورنال
عنوان ژورنال: Trends in Glycoscience and Glycotechnology
سال: 1991
ISSN: 0915-7352,1883-2113
DOI: 10.4052/tigg.3.28